2seventy bio and BMS to drop KarMMa-9 study

25 September 2024

US biotech 2seventy bio (Nasdaq: TSVT) and partner Bristol Myers Squibb (NYSE: BMS) today revealed that they will discontinue enrollment in its ongoing Phase III KarMMa-9 study.

Investors were disappointed, sending 2seventy bio’s shares down 9.2% to $4.33 in early market activity.

The trial is evaluating the biotech lead asset Abecma (idecabtagene vicleucel; ide-cel) with lenalidomide maintenance versus lenalidomide maintenance alone in patients with newly diagnosed multiple myeloma (NDMM) who have suboptimal response to autologous stem cell transplant.

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