In a second acquisition announced so far this year, global biotech leader Amgen (Nasdaq: AMGN) said yesterday that it has agreed to buy KAI Pharmaceuticals, a privately held pharmaceutical company based in South San Francisco, for a cash consideration of $315 million).
KAI's lead product candidate, KAI-4169, is a novel agent being initially studied for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) who are on dialysis. SHPT, a component of CKD mineral and bone disorder (MBD), is a common and serious complication for patients with CKD who are on dialysis.
Through this acquisition, Amgen will acquire worldwide rights, excluding Japan, to KAI-4169, excluding Japan, where the drug is out-licensed to local drugmaker Ono Pharmaceuticals (TYO: 4528; The Pharma Letter September 19, 2011). The Japanese accord earned KAI an upfront $13 million and the potential for significant - but undisclosed - development, regulatory and commercialization milestones. KAI will also receive a royalty on sales.
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